Fonte:
https://www.atsjournals.org/doi/epdf/10.1164/rccm.202202-0399ST?role=tab

Explicação do que significa declínio absoluto:

Apesar da atual definição de FPP, outros estudos usaram ou propõem novos critérios:

– The natural history of progressive fibrosing interstitial lung diseases (dados do INBUILD / INPULSIS)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315005/pdf/ERJ-00085-2020.pdf

Subjects had to meet one of the following criteria for disease progression in the 24 months before screening, as determined by the investigator, despite management as deemed appropriate in clinical practice for the individual ILD: 1) a relative decline in FVC ⩾10% predicted; 2) a relative decline in FVC ⩾5% predicted but <10% predicted and worsened respiratory symptoms; 3) a relative decline in FVC ⩾5% predicted but <10% predicted and increased extent of fibrosis on HRCT; 4) worsened respiratory symptoms and increased extent of fibrosis on HRCT.

– Lung function trajectory in progressive fibrosing interstitial lung disease, página 14 (comparação entre critérios)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039317/pdf/nihms-1780876.pdf

– Validation of Proposed Criteria for Progressive Pulmonary Fibrosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952866/pdf/rccm.202201-0124OC.pdf

– PROGRESS
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411897/pdf/ERJ-02718-2020.pdf